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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
23.33
Human Site:
T417
Identified Species:
39.49
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
T417
T
S
E
N
A
P
T
T
V
S
R
D
V
E
E
Chimpanzee
Pan troglodytes
XP_511585
968
108684
S425
H
S
L
C
S
G
S
S
A
S
K
A
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
T510
T
S
E
N
A
P
T
T
V
S
R
D
V
E
E
Dog
Lupus familis
XP_853409
975
109686
T417
T
S
E
N
A
P
T
T
V
S
Q
D
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
T419
T
S
D
N
T
P
T
T
V
S
Q
D
V
E
E
Rat
Rattus norvegicus
XP_573211
965
109012
T407
T
S
E
N
T
P
T
T
V
S
Q
D
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
V405
P
A
K
P
E
A
P
V
D
S
M
L
K
D
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
T416
D
G
L
S
Q
G
D
T
E
R
R
I
K
V
D
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
R404
S
H
P
L
P
P
V
R
K
Q
S
S
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G410
H
N
Y
N
D
G
Y
G
L
L
A
N
N
E
K
Honey Bee
Apis mellifera
XP_392044
968
110555
S405
Y
S
N
S
T
K
Q
S
L
F
S
L
Q
D
D
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
E418
P
Q
L
L
G
P
V
E
P
Q
K
H
E
D
T
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
S431
P
G
L
N
P
G
P
S
P
A
L
W
W
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
H487
S
V
D
T
T
D
L
H
Q
N
N
E
M
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
13.3
100
93.3
N.A.
80
86.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
40
100
100
N.A.
93.3
93.3
N.A.
26.6
N.A.
26.6
13.3
N.A.
40
40
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
22
8
0
0
8
8
8
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
0
8
8
8
0
8
0
0
36
0
22
15
% D
% Glu:
0
0
29
0
8
0
0
8
8
0
0
8
8
43
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
15
0
0
8
29
0
8
0
0
0
0
8
0
0
% G
% His:
15
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
8
0
0
8
0
15
0
15
0
8
% K
% Leu:
0
0
29
15
0
0
8
0
15
8
8
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% M
% Asn:
0
8
8
50
0
0
0
0
0
8
8
8
8
8
8
% N
% Pro:
22
0
8
8
15
50
15
0
15
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
8
0
8
0
8
15
22
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
22
0
0
0
0
% R
% Ser:
15
50
0
15
8
0
8
22
0
50
15
8
8
8
15
% S
% Thr:
36
0
0
8
29
0
36
43
0
0
0
0
0
0
8
% T
% Val:
0
8
0
0
0
0
15
8
36
0
0
0
36
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _